Kabilyte

KABILYTETM in a Freeflex container available in 500  and 1000ml pack size

As directed by a physician. Dosage, rate and duration of administration are to be individualized and dependent upon the indication for use, the patient’s age, weight, concomitant treatment and clinical condition of the patient as well as laboratory determinations.

After opening the container, the contents should be used immediately and should not be stored for a subsequent infusion. Do not reconnect any partially used containers.

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration whenever solution and container permit.

Do not administer unless the solution is clear and seal is intact.

KABILYTETM (Multiple Electrolytes Injection Type 1 USP) is indicated as a source of water and electrolytes or as an alkalinizing agent.

KABILYTETM (Multiple Electrolytes Injection Type 1 USP) is compatible with blood or blood components. It may be administered prior to or following the infusion of blood through the same administration set (i.e., as a priming solution), added to or infused concurrently with blood components, or used as a diluent in the transfusion of packed erythrocytes.

Description

KABILYTE^TM (Multiple Electrolytes Injection Type 1 USP) is a sterile, non-pyrogenic isotonic solution in a single dose container for intravenous administration. KABILYTE^TM (Multiple Electrolytes Injection Type 1 USP) administered intravenously has value as a source of water and electrolytes.

Composition

Each 100 ml. contains :

Sodium Chloride                                                 IP                0.526 g.

Sodium Gluconate                                              USP            0.502 g.

Sodium Acetate Trihydrate                                 IP                0.368 g.

Potassium Chloride                                            IP                0.037 g,

Magnesium Chloride Hexahydrate                     IP                0.030 g,

Water for Injections                                             IP                q.s.

It may contain Sodium Hydroxide IP or Hydrochloric Acid IP to adjust the pH.

Concentration of Electrolytes (mmoles /L)

Sodium                          140.0

Potassium                        5.0

Magnesium                      1.5

Chloride                           98.0

Acetate                            27.0

Gluconate                        23.0

Osmolarity : 294mOsm/L (Calc)

pH : 7.4(6.5 - 8.0)

Clinical Pharmacology

KABILYTE^TM (Multiple Electrolytes Injection Type 1 USP) has value as a source of water and electrolytes. It is capable of inducing diuresis depending on the clinical condition of the patient. KABILYTE^TM (Multiple Electrolytes Injection Type 1 USP) produces a metabolic alkalinizing effect. Acetate and Gluconate ions are metabolized ultimately to carbon dioxide and water, which requires the consumption of hydrogen cations