INTAXEL (Paclitaxel) is a mitotic inhibitor.
Mechanism of action:
INTAXEL (Paclitaxel USP) is a novel antimicrotubule agent that promotes the assembly of microtubules from tubulin dimers and stabilizes microtubules by preventing depolymerization. This stability results in the inhibition of normal dynamic reorganization of the microtubule network that is essential for vital interphase and mitotic cellular functions. In addition, INTAXEL (Paclitaxel USP) induces abnormal arrays or “bundles” of microtubules throughout the cell cycle and multiple asters of microtubules during mitosis.